(CW) Research Associate 2, Cork

BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions. Guided by our purpose to develop medicines that make a profound impact on people’s lives, our global teams have delivered a portfolio of therapies since our founding in 1997. Our revolutionary treatments for conditions such as achondroplasia (the most common form of dwarfism), PKU (phenylketonuria), CLN2, a form of Batten disease, and various forms of MPS (mucopolysaccharidosis) offer new possibilities for patients and families who previously had few, if any, options. More recently, the acquisition of Amicus has expanded our portfolio to include therapies for Fabry disease and Pompe disease, increasing our ability to reach more people living with rare genetic conditions.

Job Title Research Associate 2

Reports to Upstream Sr. Scientist 1

Responsibilities Laboratory / Project Work

Executes defined procedures independently to support BCoE studies and investigation activities with lab‑scale upstream processes in the multi‑product lab.

Demonstrates quick learning of core scientific techniques, principles, and protocols; owns small project portions with reliable execution and summarizes findings.

Understands the principles of aseptic operation and has experience working in biosafety cabinets.

Possesses experience in daily operations with microbial cell culture (E. coli), including:

Cell thawing

Cell banking

Seed train expansion

Has experience in fermentation processes, including:

Fermenter inoculation

Daily monitoring

Sampling

In‑process analysis utilizing standard bioprocess analytical equipment

Has a basic understanding of mammalian cell expansion and its differences compared to microbial operations.

Experience in processing of inclusion bodies is desirable.

Produces accurate, reproducible data entries and maintains laboratory quality through adherence to safety standards and SOPs; able to troubleshoot common problems with guidance.

Expands technical toolkit by adapting and troubleshooting process steps or assays; applies appropriate methods and interprets basic data trends.

Updates and refines SOP/BPD documentation.

Assists in drafting concise technical summaries.

Understanding of fed‑batch and perfusion bioprocesses is desirable.

Experience in depth filtration and ultrafiltration is desirable.

Understanding of downstream purification processes is desirable.

General Responsibilities

Executes and completes projects independently.

Generates and reviews data; performs data analysis.

Maintains up‑to‑date documentation of laboratory work, including storage and archiving in accordance with GLP.

Supports updates of lab instructions, BPDs, SOPs, and templates.

Supports maintenance and calibration of lab equipment with accompanying documentation.

Contributes to the evaluation of new equipment.

Acts as a team player with excellent communication skills.

Plays an active role in maintaining and enhancing workplace and laboratory safety.

Complies with applicable GxP regulations, SOPs, HSE, and other laboratory guidelines.

May be required to work periodically outside normal business hours, including weekends.

Key Performance Metrics

Adherence to project plans and deliverables

Adherence to applicable GxP and EHS requirements

Technical reports executed on time and to quality standards

Efficient technical exchange with Project Leads

Note: This description is not intended to be all‑inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

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