Upstream Bioprocess Scientist (Senior/Principal) - …, Limerick

The Upstream Bioprocess Scientist– TS/MS will be responsible for providing technical support for the introduction of manufacturing processes into the upstream operations/manufacturing environment in Limerick through the startup and into routine manufacturing operations. The successful applicant will have technical expertise in upstream bioprocessing and experience in data-driven decision-making and problem-solving capabilities. They will also work to continuously improve process performance by implementing new technologies and process improvements. They will maximize the benefits of a digital plant to gain in depth knowledge of the process through data analytics and process analytical technology.

Key Responsibilities

Knowledgeable of the science of upstream cell culture processes and understand molecule-specific control strategy and basis of specifications and critical attributes

Understand purpose and capability of each upstream unit operation and the impact of equipment on the process

Provide technical support to the online process support team for process science, operational excellence and compliance

Work as part of a cross-functional team at the interface between quality assurance, operations and engineering to bring deep technical expertise and scientific rigor to the team

Utilize process monitoring tools to make data driven decisions to ensure process consistency and robustness

Understand basic statistical methodologies engage with statisticians to assign specifications, validation acceptance criteria, tech transfer criteria, material sampling criteria, comparability assessments and analysis of batch data for summary reports and product reviews

Understand integration of process parameter requirements with MES/electronic batch records to ensure all regulatory, compliance and process monitoring needs are captured in manufacturing electronic documentation

Identify process improvements and participate in implementation of Lean Manufacturing initiatives

Generate scientific reports and technical documentation

Understand and ensure compliance with safety, compliance, and regulatory expectations

Contribute to the authorship and review of regulatory submissions and responses to regulatory agencies

Attributes for the Role

Demonstrated technical capability with high productivity

Proven track record of curiosity with learning agility

Self-starter with high initiative and data-driven approach to problem-solving

Demonstrated strong interpersonal skills

Demonstrated strong verbal and written communication skills

Demonstrated adaptability and flexibility to working in different environments, teams etc.

Demonstrated ability to participate in and facilitate decision-making

Educational Requirements BSc or MSc in Biochemistry, Biology, Biotechnology, Chemical Engineering or related discipline with relevant experience (>2 years’ experience within the biopharmaceutical industry)

Work Environment These are 8-hour day roles. As a manufacturing support function, the need for occasional evening or weekend support can arise.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

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